Publication of immunological and histologic results from the Phase 1/2a clinical trial of the CPCB-RPE1 implant for advanced, dry age-related macular degeneration, entitled, “Survival of an HLA-mismatched, Bioengineered RPE Implant in Dry Age-Related Macular Degeneration,” published online in Stem Cell Reports
Regenerative Patch Technologies Presents Clinical Data Demonstrating Long-Term Survival and Function of an Allogenic Bioengineered Cellular Implant in Patients with Advanced Dry Aged-Related Macular Degeneration.
Dr. Suber Huang presented the RPT study at the 2022 OIS Innovation Summit in San Antonio
Publication of the one year follow-up results from our Phase 1/2a clinical trial in dry age-related macular degeneration - In a Special Issue of Translational Vision Science & Technology (tvst)
February 8, 2022, by David Hutton
Discovery by USC investigators shows long-term viability of stem cell derived retinal implant
Read the latest blog post (or listen on Spotify) profiling our program on THE STEM CELLAR, The Official Blog of CIRM, California's Stem Cell Agency.
Dr. Amir Kashani presented results of the RPT study at the Angiogenesis 2022 conference. His Presentation was featured in Modern Retina, Feb 11, 2022
In a paper published in the journal Scientific Reports, RPT scientists in collaboration with colleagues at the University of California Santa Barbara and the University of Southern California report a novel cryopreservation technique that facilitates long-term storage of RPT’s CPCB-RPE1 ocular implants. This technique will greatly enhance the ability to widely distribute the implants and increase the number AMD patients that are able to receive the treatment.
Publication of preliminary results from our Phase 1/2a clinical trial in dry age-related macular degeneration - The cover story in Science Translational Medicine
AARP highlights RPT Study participant in: Saving Their Health and Ours. Medical Breakthroughs of 2020
A video produced by the Roski Eye Institute - highlighting the first implant procedure
A participant in our clinical trial shares her story.
Read the full article on Futurity where Researcher Mohamed Faynus discusses how the RPT stem cell-derived retinal patch survived two years post-implantation, without triggering immune rejection.
Read the full article in the Sept/Oct 2021 issue of Retina Specialist where Richard Mark Kirkner interviews Dr. Amir Kashani, about the technology and the clinical investigation.
Regenerative Patch Technologies Reports Latest Findings from Phase 1/2a Clinical Trial at 2021 International Society of Stem Cell Research Annual Meeting
Read the latest blog post (or listen on Spotify) profiling our program on THE STEM CELLAR, The Official Blog of CIRM, California's Stem Cell Agency.
In an article for UCSB - The Current, Britney Pennington and Lincoln Johnson discuss how novel cryopreservation methods enable long-term storage and worldwide distribution of a cellular therapy for age-related macular degeneration.
RPT co-founder Dr. Dennis Clegg describes the recent strategies to develop a regenerative patch for the treatment of age-related macular degeneration by developing a cellular therapy using stem cells.
TEDx talk - Stemming Vision Loss with Stem Cells- RPT co-founder Dr. Dennis Clegg
Why There’s New Hope About Ending Blindness
Highlighted in the documentary Story of Sight
Regenerative Patch Technologies Reports the Findings from Phase 1/2a clinical trial at 2023 International Society of Stem Cell Research Annual Meeting
Advancing A Bio-Engineered Implant for Improvement of Vision
Dr. Hani Salehi-Had presents at the American Society of Retina Specialists Annual Meeting, October 2021
Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration. Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C, Palejwala N, Ingram A, Dang W, Lin CM, Mitra D, Martinez-Camarillo JC, Bailey J, Arnold C, Pennington BO, Rao N, Johnson LV, Clegg DO, Humayun MS. Stem Cell Reports. 2022 Mar 8;17(3):448-458.
One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration. Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W, Lin CM, Mitra D, Pennington BO, Hinman C, Faynus MA, Bailey JK, Mohan S, Rao N, Johnson LV, Clegg DO, Hinton DR, Humayun MS. Transl Vis Sci Technol. 2021 Aug 12;10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, Johnson LV, Clegg DO. Sci Rep. 2021 Mar 18;11(1):6286.
Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Ophthalmol Retina. 2020 Mar;4(3):264-273.
Kashani AH, Martynova A, Koss M, Brant R, Zhu DH, Lebkowski J, Hinton D, Clegg D, Humayun MS.
Adv Exp Med Biol. 2019;1185:569-574.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS. Sci Transl Med. 2018 Apr 4;10(435). pii: eaao4097.
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