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Highlights from the Podium and In the News

Publication of Immunological and Histologic Results in Stem Cell Reports

Publication of Immunological and Histologic Results in Stem Cell Reports

Publication of Immunological and Histologic Results in Stem Cell Reports

Publication of immunological and histologic results from the Phase 1/2a clinical trial of the CPCB-RPE1 implant for advanced, dry age-related macular degeneration, entitled, “Survival of an HLA-mismatched, Bioengineered RPE Implant in Dry Age-Related Macular Degeneration,”  published online in Stem Cell Reports

Read the full article here

Press Release 4 February 2022

Publication of Immunological and Histologic Results in Stem Cell Reports

Publication of Immunological and Histologic Results in Stem Cell Reports

Regenerative Patch Technologies Presents Clinical Data Demonstrating Long-Term Survival and Function of an Allogenic Bioengineered Cellular Implant in Patients with Advanced Dry Aged-Related Macular Degeneration.

Download the full release here

Presentation at 2022 OIS Innovation Summit

Publication of Immunological and Histologic Results in Stem Cell Reports

Publication of One-Year Follow-Up Results of Phase 1/2a Clinical Trial

 Dr. Suber Huang presented the RPT study at the 2022 OIS Innovation Summit in San Antonio  

Watch Dr. Huang's presentation Here

Publication of One-Year Follow-Up Results of Phase 1/2a Clinical Trial

THE STEM CELLAR How a tiny patch is helping restore lasting vision

Publication of One-Year Follow-Up Results of Phase 1/2a Clinical Trial

 Publication of the one year follow-up results from our Phase 1/2a clinical trial in dry age-related macular degeneration - In a Special Issue of Translational Vision Science & Technology (tvst)  

Read the full article here

RPT Featured in Ophthalmology Times

THE STEM CELLAR How a tiny patch is helping restore lasting vision

THE STEM CELLAR How a tiny patch is helping restore lasting vision

February 8, 2022, by  David Hutton

Discovery by USC investigators shows long-term viability of stem cell derived retinal implant

Read the full article here

THE STEM CELLAR How a tiny patch is helping restore lasting vision

THE STEM CELLAR How a tiny patch is helping restore lasting vision

THE STEM CELLAR How a tiny patch is helping restore lasting vision

Read the latest blog post (or listen on Spotify) profiling our program on  THE STEM CELLAR, The Official Blog of CIRM, California's Stem Cell Agency.

Read or listen to the full article here

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

Dr. Amir Kashani presented results of the RPT study at the Angiogenesis 2022 conference.  His Presentation was featured in Modern Retina, Feb 11, 2022

Read the full article here

Publication in Scientific Reports

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

  In a paper published in the journal Scientific Reports, RPT scientists in collaboration with colleagues at the University of California Santa Barbara and the University of Southern California report a novel cryopreservation technique that facilitates long-term storage of RPT’s CPCB-RPE1 ocular implants. This technique will greatly enhance the ability to widely distribute the implants and increase the number AMD patients that are able to receive the treatment. 

Read the full article here

Publication in Science and Translational Medicine

RPT Presentation at Angiogenesis 2022 Featured in Modern Retina

Publication in Science and Translational Medicine

Publication of preliminary results from our Phase 1/2a clinical trial in dry age-related macular degeneration - The cover story in Science Translational Medicine  

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AARP - Medical Breakthroughs of 2020

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

Publication in Science and Translational Medicine

AARP highlights RPT Study participant in:   Saving Their Health and Ours.  Medical Breakthroughs of 2020

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First Step

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

A video produced by the Roski Eye Institute - highlighting the first implant procedure

Click to Watch

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

Hope is in Sight for Dry AMD: First-in-Kind Stem Cell-Based Retinal Implant

A participant in our clinical trial shares her story.

Click to Watch

RPT Stem Cell Patch Profiled on Futurity

Clinical Trial Close-Up in the latest issue of Retina Specialist

Clinical Trial Close-Up in the latest issue of Retina Specialist

Read the full article on Futurity where Researcher Mohamed Faynus discusses how the RPT stem cell-derived retinal patch survived two years post-implantation,  without triggering immune rejection.

Read the full article here

Clinical Trial Close-Up in the latest issue of Retina Specialist

Clinical Trial Close-Up in the latest issue of Retina Specialist

Clinical Trial Close-Up in the latest issue of Retina Specialist

Read the full article in the Sept/Oct 2021 issue of Retina Specialist where Richard Mark Kirkner interviews Dr. Amir Kashani, about the technology and the clinical investigation. 

Read the full article here

Press Release 21 June 2021

Clinical Trial Close-Up in the latest issue of Retina Specialist

THE STEM CELLAR Sometimes a cold stare is a good thing

Regenerative Patch Technologies Reports Latest Findings from Phase 1/2a Clinical Trial at 2021 International Society of Stem Cell Research Annual Meeting 

Download the full release here

THE STEM CELLAR Sometimes a cold stare is a good thing

THE STEM CELLAR Sometimes a cold stare is a good thing

THE STEM CELLAR Sometimes a cold stare is a good thing

Read the latest blog post (or listen on Spotify) profiling our program on  THE STEM CELLAR, The Official Blog of CIRM, California's Stem Cell Agency.

Read the full post here

University of California Santa Barbara - The Current

THE STEM CELLAR Sometimes a cold stare is a good thing

University of California Santa Barbara - The Current

In an article for UCSB - The Current, Britney Pennington and Lincoln Johnson discuss how novel cryopreservation methods enable long-term storage and worldwide distribution of a cellular therapy for age-related macular degeneration. 

Read the full article here

Vision for the Future: Stem Cell Therapy for Eye Disease

Vision for the Future: Stem Cell Therapy for Eye Disease

Vision for the Future: Stem Cell Therapy for Eye Disease

RPT co-founder Dr. Dennis Clegg describes the recent strategies to develop a regenerative patch for the treatment of age-related macular degeneration by developing a cellular therapy using stem cells. 

Click to watch

TEDx talk - Stemming Vision Loss with Stem Cells

Vision for the Future: Stem Cell Therapy for Eye Disease

Vision for the Future: Stem Cell Therapy for Eye Disease

TEDx talk - Stemming Vision Loss with Stem Cells-  RPT co-founder Dr. Dennis Clegg    


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Featured in National Geographic

Featured in National Geographic

Featured in National Geographic

Why There’s New Hope About Ending Blindness  

Find out more

The Story of Sight

Featured in National Geographic

Featured in National Geographic

Highlighted in the documentary Story of Sight 

Click to see a preview

RPT Reports Latest Findings from Phase 1/2a Clinical Trial

 Regenerative Patch Technologies Reports the Findings from Phase 1/2a clinical trial at 2023 International Society of Stem Cell Research Annual Meeting  

Download The Presentation

From the Podium

Advancing A Bio-Engineered Implant for Improvement of Vision

 Dr.  Hani Salehi-Had presents at the American Society of Retina Specialists Annual Meeting, October 2021 

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publications

 Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.  Kashani AH, Lebkowski  JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had  H, Chan C, Palejwala N, Ingram A, Dang W, Lin CM, Mitra D,  Martinez-Camarillo JC, Bailey J, Arnold C, Pennington BO, Rao N, Johnson  LV, Clegg DO, Humayun MS. Stem Cell Reports. 2022 Mar 8;17(3):448-458.  


 One-Year Follow-Up in a Phase 1/2a Clinical Trial of an  Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related  Macular Degeneration.    Kashani AH, Lebkowski  JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N,  Ingram A, Dang W, Lin CM, Mitra D, Pennington BO, Hinman C, Faynus MA,  Bailey JK, Mohan S, Rao N, Johnson LV, Clegg DO, Hinton DR, Humayun MS. Transl Vis Sci Technol. 2021 Aug 12;10(10):13. 


Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.  

Pennington BO, Bailey JK,  Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D,  Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS,  Lebkowski J, Johnson LV, Clegg DO. Sci Rep. 2021 Mar 18;11(1):6286. 


Surgical  Method for Implantation of a Biosynthetic Retinal Pigment Epithelium  Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.

Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Ophthalmol Retina. 2020 Mar;4(3):264-273. 


Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model.

Kashani AH, Martynova A, Koss M, Brant R, Zhu DH, Lebkowski J, Hinton D, Clegg D, Humayun MS.

Adv Exp Med Biol. 2019;1185:569-574. 


A Bioengineered Retinal Pigment Epithelial Monolayer for Advanced, Dry Age-Related Macular Degeneration.

Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D,  Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS. Sci Transl Med. 2018 Apr 4;10(435). pii: eaao4097. 


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